Stefano Panzeri

Senior Researcher Tenured - Center Coordinator
Director of the Neural Computation Laboratory; Center Coordinator

Research Lines

Neural Computation

Contacts

Italian Institute of TechnologyCenter for Neuroscience and Cognitive Systems @ UniTn, Corso Bettini 31, Rovereto (Tn)

About

Stefano Panzeri received a Laurea in Physics from the University of Torino, and a PhD in Computational Neuroscience from SISSA, Trieste, Italy.

He has held personal Research Fellowship awards in both theoretical physics and computational neuroscience, including an INFN junior Fellowship in Theoretical Physics at Turin University, an EU Marie Curie postdoctoral Fellowship at the University of Oxford, and an MRC Research Fellowship in Neuroinformatics at the University of Newcastle. He has held tenured Faculty positions as assistant, associate and full professor at the Universities of Manchester and Glasgow. He has been visiting scientist at the Max Planck Institute for Biological Cybernetics and at Harvard Medical School. He served as Deputy Chair of the UK Medical Research Council panel for fellowships in Bioinformatics and Neuroinformatics; as a member of the UK EPSRC Review College, and as an editor of the journal Frontiers in Systems Neuroscience and of Journal of Neuroscience methods. 

His research lies at the interface between theory and experiment and aims at understanding the principles of cortical information processing by developing new quantitative data analysis techniques based on the principles of Information Theory and by developing computational models of neural network function. At IIT, he works as Senior Scientist (with Tenure) and directs the Laboratory of Neural Computation. He also currently serves as Coordinator of the Center for Neuroscience and Cognitive Systems of the IIT in Rovereto.

Selected Publications

Zaldivar, D., Goense, J., Lowe, S.C., Logothetis, N.K., and Panzeri, S. (2018) Dopamine Is Signaled by Mid-frequency Oscillations and Boosts Output Layers Visual Information in Visual Cortex. Current Biology 28: 224-235, https://doi.org/10.1016/j.cub.2017.12.006.

Pica, G., Piasini, E., Safaai, H., Runyan, C.A., Diamond, M.E., Fellin, T., Kayser, C., Harvey, C.D., and Panzeri, S. (2017) Quantifying how much sensory information in a neural code is relevant for behavior Neural Information Processing Systems (NIPS 2017) ,in press.

Runyan C. A., Piasini E., Panzeri S*., Harvey C. D*. (2017) Distinct timescales of population coding across cortex, Nature: 548: 92-96 * = co-corresponding author

Liu J. K., Schreyer, Onken A., Rozenblit F., Hossein Khani M., Krishnamoorthy V, Panzeri S., Gollisch T. (2017) Inference of neuronal functional circuitry with spike-triggered non-negative matrix factorization, Nature Communications 8: 149 

Giordano B. L., Ince R. A. A., Gross J., Schyns P. G., Panzeri S., Kayser C. (2017) Contributions of local speech encoding and functional connectivity to audio-visual speech perception, eLIFE, vol. 6, pp. e24763

Zucca S., D'Urso G., Pasquale V., Vecchia D., Pica G., Bovetti S., Moretti C., Varani S., Molano Mazon M., Chiappalone M., Panzeri S., Fellin T. (2017) An inhibitory gate for state transition in cortex, eLIFE 6:. e26177 

S. Tafazoli, H. Safaai, G. De Franceschi, FB Rosselli, W Vanzella, M Riggi, F Buffolo, S Panzeri and D Zoccolan (2017) Emergence of transformation-tolerant representations of visual objects in rat lateral extrastriate cortex. eLIFE 6: e22794

S. Panzeri, C.D. Harvey, E. Piasini, P.E. Latham, T. Fellin, (2017) Cracking the neural code for sensory perception by combining statistics, intervention and behaviour. Neuron 93: 491-507

Onken A., Panzeri S. (2016) Mixed vine copulas as joint models of spike counts and local field potentials. Advances in Neural Information Processing Systems 29 (NIPS 2016) 1325–1333

Onken A, Liu JK, Karunasekara PPCR, Delis I, Gollisch T, Panzeri S (2016) Using Matrix and Tensor Factorizations for the Single-Trial Analysis of Population Spike Trains. PLoS Comput Biol 12(11): e1005189.

D Fasoli, A. Cattani, S. Panzeri (2016) The complexity of dynamics in small neural circuits. PLoS Computational Biology, 12(8): e1004992.

H. Safaai, R Neves, O Eschenko, NK Logothetis, S Panzeri (2015) Modelling the effect of Locus Coeruleous firing on single trial cortical state dynamics and sensory processing. Proc. Natl. Acad. Sci. USA 112(41): 12834–12839

Besserve M, Lowe S, Logothetis NK, Scholkopf B, Panzeri S (2015) Shifts of gamma phase across primary visual cortical sites reflect dynamic stimulus- modulated information transfer. PLoS Biology  13(9): e1002257

Kayser C., Wilson C., Safaai H., Sakata S., Panzeri S. (2015) Rhythmic Auditory Cortex Activity at Multiple Timescales Shapes Stimulus–Response Gain and Background Firing. Journal of Neuroscience 35(20): 7750 –7762

S. Panzeri, J.H. Macke, J. Gross, C. Kayser (2015) Neural population coding: combining insights from microscopic and mass signals, Trends in Cognitive Sciences 19: 162-172

Y. Zuo, H. Safaai, G. Notaro, A. Mazzoni, S. Panzeri*, M.E. Diamond* (2015) Complementary Contributions of Spike Timing and Spike Rate to Perceptual Decisions in Rat S1 and S2 Cortex. Current Biology 25: 357-363            *equal senior author contribution

Einevoll, Kayser C., Logothetis N. K., Panzeri S. (2013) Modelling and analysis of local field potentials for studying the function of cortical circuits, Nature Reviews Neuroscience, vol. 14, pp. 770-785

Gross J., Hoogenboom N, Thut G., Schyns P. S., Panzeri S., Belin P., Garrod S. (2013) Speech Rhythms and Multiplexed Oscillatory Sensory Coding in the Human Brain, PLoS Biology, pp. e1001752

Kayser C, Ince RAA, Panzeri S (2012). Analysis of slow (theta) oscillations as a potential temporal reference frame for information coding in sensory cortices. PLoS Computational Biology 8 (10), e1002717

Kayser C, Logothetis NK, Panzeri S (2010) The millisecond encoding precision of auditory cortex neurons. Proc. Natl. Acad. Sci. USA 107: 16976–16981

Mazzoni A, Whittingstall K, Brunel N, Logothetis NK, Panzeri S (2010) Understanding the relationships between spike rate and delta/gamma frequency bands of LFPs and EEGs using a local cortical network model. Neuroimage 52: 956–972

Kayser C, Logothetis NK, Panzeri S (2010) Visual enhancement of the information representation in auditory cortex. Current Biology 20: 19-24 

Quian Quiroga R, Panzeri S (2009) Extracting information from neuronal populations: information theory and decoding approaches. Nature Reviews Neuroscience 10: 173-185

Kayser C, Montemurro MA, Logothetis NK, Panzeri S (2009) Auditory information coding is boosted by nested spike-phase and spike-pattern codes. Neuron 61: 597-608

Belitski A, Gretton A, Magri C, Murayama Y, Montemurro MA, Logothetis NK, Panzeri S (2008) Low-frequency local field potentials and spikes in primary visual cortex convey independent visual information. J Neurosci 28: 5696-5709

Montemurro MA, Rasch MJ, Murayama Y, Logothetis NK, Panzeri S (2008) Phase-of-firing coding of natural visual stimuli in primary visual cortex. Current Biology 18: 375-380

Panzeri S, Petersen R, Schultz SR, Lebedev M, Diamond ME (2001) The role of spike timing in the coding of stimulus location in rat somatosensory cortex. Neuron 29: 769-777 

iit Publications

2018 Dopamine Is Signaled by Mid-frequency Oscillations and Boosts Output Layers Visual Information in Visual Cortex
2017 An inhibitory gate for state transition in cortex
2017 Biofeedback Signals for Robotic Rehabilitation: Assessment of Wrist Muscle Activation Patterns in Healthy Humans
2017 Brainwide mapping of spontaneous network dynamics in the mouse brain
2017 Cholinergic Control of Information Coding
2017 Contributions of local speech encoding and functional connectivity to audio-visual speech perception
2017 Cracking the Neural Code for Sensory Perception by Combining Statistics, Intervention, and Behavior
2017 Distinct timescales of population coding across cortex
2017 Dynamic reconfiguration of spontaneous network activity in the mouse brain
2017 Effects of ambient luminance on retinal information coding
2017 Effects of Attention on Visual Processing between Cortical Layers and Cortical Areas
2017 Emergence of transformation-tolerant representations of visual objects in rat lateral extrastriate cortex
2017 Homozygous loss of autism-risk gene CNTNAP2 results in reduced local and long-range prefrontal functional connectivity
2017 Inference of neuronal functional circuitry with spike-triggered non-negative matrix factorization
2017 Information Jitter Derivative Method: A Novel Approach to the Analysis of Multiplexed Neural Codes.
2017 Invariant components of synergy, redundancy, and unique information among three variables
2017 Layer dependent attentional modulation of broad and narrow spiking cells in primate V1
2017 Natural Translating Locomotion Modulates Cortical Activity at Action Observation
2017 Quantifying how much sensory information in a neural code is relevant for behavior
2017 Quantifying how much sensory information in a neural code is relevant for behavior
2017 State-dependent decoding algorithms improve the performance of a bidirectional bmi in anesthetized rats
2017 Synergy and redundancy in dual decompositions of mutual information gain and information loss
2017 The spectrum of asynchronous dynamics in neocortical networks
2017 Transitions between asynchronous and synchronous states: a theory of correlations in small neural circuits
2017 What Do Neurons Communicate to Each Other?
2016 A Novel Approach to the Analysis of Multiplexed Neural Codes
2016 Attention induced gain stabilization in broad and narrow- spiking cells in the frontal eye-field of macaque monkeys
2016 Choice probabilities in the presence of nonzero signal stimuli, internal bias, and decision feedback
2016 Directed information flow in fMRI connectivity
2016 Directed information flow in fMRI connectivity networks
2016 Directed information flow in fMRI connectivity networks
2016 Implications of the dependence of neuronal activity on neural network states for the design of brain-machine interfaces
2016 Intrinsic directional connectivity in large-scale functional networks of the mouse brain
2016 Mixed vine copulas as joint models of spike counts and local field potentials
2016 Space-by-time decomposition for single-trial decoding of M/EEG activity
2016 Space-by-time manifold representation of dynamic facial expressions for emotion categorization
2016 The Complexity of Dynamics in Small Neural Circuits
2016 The Deceptively Simple N170 Reflects Network Information Processing Mechanisms Involving Visual Feature Coding and Transfer Across Hemispheres
2016 Unaltered Network Activity and Interneuronal Firing during Spontaneous Cortical Dynamics in Vivo in a Mouse Model of Severe Myoclonic Epilepsy of Infancy
2016 Using Matrix and Tensor Factorizations for the Single-Trial Analysis of Population Spike Trains
2015 A bidirectional brain-machine interface connecting alert rodents to a dynamical system
2015 A Formalism for evaluating analytically the cross-correlation structure of a firing-rate network model
2015 Analysis of Multiplexed Neural Codes Using the Laplacian Pyramid Decomposition
2015 Complementary contributions of spike timing and spike rate to perceptual decisions in rat S1 and S2 cortex
2015 Computing the Local Field Potential (LFP) from Integrate-and-Fire Network Models
2015 Directed functional connectivity mapping in the mouse brain
2015 Extracting information in spike time patterns with wavelets and information theory
2015 MAPPING EFFECTIVE CONNECTIVITY IN THE MOUSE BRAIN USING GRANGER CAUSALITY
2015 Modeling the effect of locus coeruleus firing on cortical state dynamics and single-trial sensory processing
2015 Neural population coding: Combining insights from microscopic and mass signals
2015 Rhythmic auditory cortex activity at multiple timescales shapes stimulus–response gain and background firing
2015 Shifts of Gamma Phase across Primary Visual Cortical Sites Reflect Dynamic Stimulus-Modulated Information Transfer
2015 Spike time based unsupervised learning of receptive fields for event-driven vision
2015 Task-discriminative space-by-time factorization of muscle activity
2015 Tracing the Flow of Perceptual Features in an Algorithmic Brain Network
2015 What can neuromorphic event-driven precise timing add to spike-based pattern recognition?
2014 A bidirectional brain-machine interface algorithm that approximates arbitrary force-fields
2014 A dynamical systems model of the effect of Locus Coeruleus firing on single trial cortical state dynamics
2014 Algorithms of causal inference for the analysis of effective connectivity among brain regions
2014 Applications of Information Theory to Analysis of Neural Data
2014 A unifying model of concurrent spatial and temporal modularity in muscle activity
2014 Brain function: Novel technologies driving novel understanding
2014 Comparison of the dynamics of neural interactions between current-based and conductance-based integrate-and-fire recurrent networks
2014 Estimating Information-Theoretic Quantities
2014 Hierarchical flow of sensory information in rat somatosensory cortex
2014 Local Field Potential, Relationship to BOLD Signal
2014 Modulation of correlation by activity levels: from synaptic currents to single neurons and population activity
2014 Reading spike timing without a clock: Intrinsic decoding of spike trains
2014 Slow activity fluctuations alter the decoding strategies of an ideal observer
2014 Stimulus dependence of local field potential spectra: Experiment versus theory
2014 Summary of Information Theoretic Quantities
2013 A methodology for assessing the effect of correlations among muscle synergy activations on task-discriminating information
2013 Assessing the role of synchronization and phase coherence in neural communication comparing cortical recordings and integrate-and-fire network models
2013 Decoding and information theory in neuroscience
2013 Information content of Local Field Potentials: experiments and models
2013 Investigating reduction of dimensionality during single-joint elbow movements: A case study on muscle synergies
2013 Modelling and analysis of local field potentials for studying the function of cortical circuits
2013 Muscle synergies in neuroscience and robotics: From input-space to task-space perspectives
2013 Neural codes formed by small and temporally precise populations in auditory cortex
2013 Principles of Neural Coding
2013 Quantitative evaluation of muscle synergy models: A single-trial task decoding approach
2013 Speech Rhythms and Multiplexed Oscillatory Sensory Coding in the Human Brain
2012 Analysis of Slow (Theta) Oscillations as a Potential Temporal Reference Frame for Information Coding in Sensory Cortices
2012 A novel test to determine the significance of neural selectivity to single and multiple potentially correlated stimulus features
2012 Neurons with stereotyped and rapid responses provide a reference frame for relative temporal coding in primate auditory cortex
2012 Noradrenergic neurons of the locus coeruleus are phase locked to cortical up-down states during sleep
2012 Optimal band separation of extracellular field potentials
2012 PPy-CNTs coating increases the sensitivity of extracellular neuronal recordings in vivo
2012 Shaping the dynamics of a bidirectional neural interface
2012 The amplitude and timing of the BOLD signal reflects the relationship between local field potential power at different frequencies
2011 Carbon nanotube composite coating of neural microelectrodes preferentially improves the multiunit signal-to-noise ratio
2011 Cortical dynamics during naturalistic sensory stimulations: Experiments and models
2011 Dynamic brain-machine interface: A novel paradigm for bidirectional interaction between brains and dynamical systems
2011 Investigating static nonlinearities in neurovascular coupling
2011 The laminar and temporal structure of stimulus information in the phase of field potentials of auditory cortex
2010 Causal relationships between frequency bands of extracellular signals in visual cortex revealed by an information theoretic analysis
2010 Information carried by population spike times in the whisker sensory cortex can be decoded without knowledge of stimulus time
2010 Information-theoretic methods for studying population codes
2010 Millisecond encoding precision of auditory cortex neurons
2010 Naturalistic stimulus trains evoke reproducible subicular responses both within and between animals in vivo
2010 New perspectives on the dialogue between brains and machines
2010 Open source tools for the information theoretic analysis of neural data
2010 Population Coding
2010 Sensory information in local field potentials and spikes from visual and auditory cortices: Time scales and frequency bands
2010 Sensory input drives multiple intracellular information streams in somatosensory cortex
2010 Sensory neural codes using multiplexed temporal scales
2010 Testing methodologies for the nonlinear analysis of causal relationships in neurovascular coupling
2010 Understanding the relationships between spike rate and delta/gamma frequency bands of LFPs and EEGs using a local cortical network model
2010 Visual Enhancement of the Information Representation in Auditory Cortex
2009 A global sensitivity index for biophysically detailed cardiac cell models: A computational approach
2009 A toolbox for the fast information analysis of multiple-site LFP, EEG and spike train recordings
2009 Extracting information from neuronal populations: Information theory and decoding approaches
2009 Information content and robustness of various types of codes in integrate and fire networks presented with naturalistic stimuli
2009 Neural coding and contextual influences in the whisker system
2009 On the presence of high-order interactions among somatosensory neurons and their effect on information transmission
2009 Python for information theoretic analysis of neural data
2009 Spike-Phase Coding Boosts and Stabilizes Information Carried by Spatial and Temporal Spike Patterns
2009 The impact of high-order interactions on the rate of synchronous discharge and information transmission in somatosensory cortex
2008 Decoding population neuronal responses by topological clustering
2008 Diverse and Temporally Precise Kinetic Feature Selectivity in the VPm Thalamic Nucleus
2008 Encoding of naturalistic stimuli by local field potential spectra in networks of excitatory and inhibitory neurons
2008 Information-theoretic sensitivity analysis: A general method for credit assignment in complex networks
2008 Low-frequency local field potentials and spikes in primary visual cortex convey independent visual information
2008 On the use of information theory for the analysis of the relationship between neural and imaging signals
2008 Phase-of-Firing Coding of Natural Visual Stimuli in Primary Visual Cortex
2008 Topological clustering of synchronous spike trains
2007 A downward biased estimator of spike timing information
2007 Correcting for the sampling bias problem in spike train information measures
2007 GABAergic excitation in striatal projection neurons: Simulations and experiments
2007 Role of precise spike timing in coding of dynamic vibrissa stimuli in somatosensory thalamus
2007 Spatio-temporal prediction and inference by V1 neurons
2006 Deciphering the spike train of a sensory neuron: Counts and temporal patterns in the rat whisker pathway
2006 Erratum: Deciphering the spike train of a sensory neuron: Counts and temporal patterns in the rat whisker pathway (Journal of Neuroscience (September 6, 2006) (9216-9226))
2006 Excitatory GABAergic effects in striatal projection neurons
2006 Optimal tuning widths in population coding of periodic variables
2006 Stimulus specificity of cortico-cortical connections optimizes information transmission
2005 Data-robust tight lower bounds to the information carried by spike times of a neuronal population
2005 Optimal information decoding from neuronal populations with specific stimulus selectivity
2005 Optimal information transmission through cortico-cortical synapses
2004 Exploring structure-function relationships in neocortical networks by means of neuromodelling techniques
2004 Functional imaging and neural information coding
2004 Whisker vibration information carried by rat barrel cortex neurons
2003 An exact method to quantify the information transmitted by different mechanisms of correlational coding
2003 Coding of sensory signals by neuronal populations: The role of correlated activity
2003 Correlations, feature-binding and population coding in primary visual cortex
2003 Decoding neuronal population activity in rat somatosensory cortex: Role of columnar organization
2003 Investigations into the organization of information in sensory cortex
2002 A critical assessment of different measures of the information carried by correlated neuronal firing
2002 Comparing the information encoded by different brain areas with functional imaging techniques
2002 Functional imaging and neuronal information processing
2002 Population coding in somatosensory cortex
2002 Signalling properties of bursts and spikes in model thalamic relay cells
2002 The role of individual spikes and spike patterns in population coding of stimulus location in rat somatosensory cortex
2001 A unified approach to the study of temporal, correlational, and rate coding
2001 Hierarchical organization and neuronal response latencies in the primate visual system
2001 Objective assessment of the functional role of spike train correlations using information measures
2001 Population coding of stimulus location in rat somatosensory cortex
2001 Simultaneity of responses in a hierarchical visual network
2001 Speed of feedforward and recurrent processing in multilayer networks of integrate-and-fire neurons
2001 Temporal correlations and neural spike train entropy
2001 The role of spike timing in the coding of stimulus location in rat somatosensory cortex
2000 A population code with added grandmothers?
1999 Correlated firing and the information represented by neurons in short epochs
1999 Correlations and the encoding of information in the nervous system
1999 Firing rate distributions and efficiency of information transmission of inferior temporal cortex neurons to natural visual stimuli
1999 Head direction cells in the primate pre-subiculum
1999 On Decoding the Responses of a Population of Neurons from Short Time Windows
1999 The neurophysiology of backward visual masking: Information analysis
1998 Information about spatial view in an ensemble of primate hippocampal cells
1997 Analogue resolution in a model of the schaffer collaterals
1997 Effective actions for finite temperature lattice gauge theories
1997 Finite temperature lattice QCD in the large N limit
1997 How well can we estimate the information carried in neuronal responses from limited samples?
1997 Information in the neuronal representation of individual stimuli in the primate temporal visual cortex
1996 Analytical estimates of limited sampling biases in different information measures
1996 Speed, noise, information and the graded nature of neuronal responses
1996 Toward an analytic determination of the deconfinement temperature in SU(2) lattice gauge theory
1995 Deconfinement transition in large-N lattice gauge theory
1994 Two-dimensional QCD is a one-dimensional Kazakov-Migdal model
1993 Kazakov-Migdal induced gauge theory and the coupling of 2d quantum gravity to d=1 matter
1993 The Kazakov-Migdal model as a high temperature lattice gauge theory
1992 Exact solution of D = 1 Kazakov-Migdal induced gauge theory

Awards

 

1991, Graduated Summa Cum Laude and Special Distinction, University of Torino, Italy, 1991

1992: Italian National Institute for Nuclear Physics (INFN) Prize Studentship in Theoretical Physics (Personal Research Training Award), with second place in the national competition

1997: EU Marie Curie Postdoctoral Fellowship (Personal Research Training Award)

2001: UK Medical Research Council (MRC) Research Fellowship in Neuroinformatics (Personal Research Career Award)

2005-2009 Deputy Chair of the UK’s Medical Research Council (MRC) Panel for Biomedical Informatics (major funding agency’s grant-award panel)

2005-2009 Member of the UK’s Engineering and Physics Research Council (EPSRC) Grant Review Panel (major funding agency’s grant-award panel)

2010-2015: Max Planck society Honorary Visiting Scholar – Max Planck Institute for Biological Cybernetics, Tuebingen

2015 and 2016: Bertarelli Foundation Visiting Scholar, Harvard Medical School, Neurobiology Department